Performance of the ESC 0/2h-algorithm using high-sensitivity cardiac troponin I in the early diagnosis of myocardial infarction - Koechlin, L.; Boeddinghaus, J.; Nestelberger, T.; Lopez-Ayala, P.; Wussler, D.; Shrestha, S.; Resa, T.; Wildi, K.; Bakula, A.; Frey, S.; Miro, O.; Martin-Sanchez, F. J.; et al. (Am Heart J, 2021)
The 2020 guidelines of the European Society of Cardiology (ESC) recommend a novel ESC 0/2h-algorithm as the preferred alternative to the ESC 0/1h-algorithm in the early triage for rule-out and/or rule-in of Non-ST-segment-elevation myocardial infarction (NSTEMI). The aim was to prospectively validate the performance of the ESC 0/2h-algorithm using the high-sensitivity cardiac troponin I (hs-cTnI) assay (ARCHITECT) in an international, multicenter diagnostic study enrolling patients presenting with acute chest discomfort to the emergency department.
Keywords: journalArticle; *Algorithms; *Myocardial Infarction/blood/diagnosis; *Troponin I/blood; Biomarkers/blood; Early Diagnosis; Humans; Predictive Value of Tests; Prospective Studies; Reproducibility of Results